LMNA

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核纤层蛋白 A/C英语:Lamin A/C)是由人类基因LMNA编码的蛋白质,属于核纤层蛋白家族。
核纤层蛋白 A/C英语:Lamin A/C)是由人类基因LMNA编码的蛋白质,属于核纤层蛋白家族。[1] 
核纤层蛋白 A/C
  Lamin A/C

  

  

  

  PDBrendering based on 1ifr.
有效结构
PDB直系同源检索:PDBe,RCSB
[隐藏]PDB查询代码列表
1IFR,1IVT,1X8Y,2XV5,2YPT,3GEF,3V4Q,3V4W,3V5B
标识
  

  

  
代号LMNA; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; PRO1
扩展标识遗传学:150330鼠基因:96794同源基因:41321ChEMBL:1293235GeneCards:LMNA Gene
[隐藏]基因本体论描述
分子功能·structural molecule activity
  ·protein binding
细胞成分·nucleus
·nuclear envelope
  ·lamin filament
  ·nuclear lamina
  ·nucleoplasm
  ·cytoplasm
  ·cytosol
  ·intermediate filament
·perinuclear region of cytoplasm
生物过程·M phase of mitotic cell cycle
·mitotic prophase
  ·mitotic anaphase
  ·mitotic cell cycle
  ·apoptotic process
  ·cellular component disassembly involved in execution phase of apoptosis
  ·activation of signaling protein activity involved in unfolded protein response
  ·mitotic nuclear envelope disassembly
  ·mitotic nuclear envelope reassembly
  ·muscle organ development
  ·regulation of cell migration
  ·establishment or maintenance of microtubule cytoskeleton polarity
  ·endoplasmic reticulum unfolded protein response
  ·protein localization to nucleus
  ·sterol regulatory element binding protein import into nucleus
  ·regulation of apoptotic process
  ·cellular protein metabolic process
  ·ventricular cardiac muscle cell development
  ·cellular response to hypoxia
·positive regulation of cell aging
Sources:Amigo/QuickGO
RNA表达模式
  

  

  
更多表达数据
直系同源体
  

  

  
物种人类鼠类
  
Entrez400016905
  
EnsemblENSG00000160789ENSMUSG00000028063
  
UniProtP02545P48678
  
mRNA序列NM_001257374NM_001002011
  
蛋白序列NP_001244303NP_001002011
  
基因位置Chr 1:
  156.05 – 156.11 Mb
Chr 3:
  88.48 – 88.51 Mb

  
[1] 
参考资料
  • 1.    LMNA  .维基百科[引用日期2014-06-22]